GSK256073

MedChem Express

GSK256073 [862892-90-8]

9

862892-90-8

Research Use Only

99.11

C10H13ClN4O2

256.69

GSK256073 is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC 50 of 7.5 (human HCA2). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia [1] [2] . GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2

O=C(N(C1=C2NC(Cl)=N1)CCCCC)NC2=O

-20°C,2°C to 8°C

12352200