GSK2606414
S7307
CAS Number1337531-36-8
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameGSK2606414
- Delivery Days Customer9
- CAS Number1337531-36-8
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionGSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed. GSK2606414 impairs GANT-61 induced autophagy in NB cells with MYCN amplification. GSK2606414 exacerbates ER stress-induced apoptosis in HCT116 cells while reduces the apoptosis in SIL1 KD HeLa cells.
- Storage Instruction-80°C
- UNSPSC51202000
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