GSK2945 hydrochloride
HY-117147A
Overview
- SupplierMedChem Express
- Product NameGSK2945 hydrochloride
- Delivery Days Customer10
- Estimated Purity99.79%
- Molecular FormulaC20H19Cl3N2O2S
- Molecular Weight457.8
- Scientific DescriptionGSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist with EC50s of 21.5 microM and 20.8 microM, respectively. GSK2945 hydrochloride enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism.
- SMILES[H]Cl.O=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-]
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200