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ProductsBack/GSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody

GSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody

GTX132997
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetGSK3B
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Overview

  • Supplier
    GeneTex
  • Product Name
    GSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.13 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2932
  • Target name
    GSK3B
  • Target description
    glycogen synthase kinase 3 beta
  • Target synonyms
    glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49841
  • Protein Name
    Glycogen synthase kinase-3 beta
  • Scientific Description
    Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Electroacupuncture improves TBI dysfunction by targeting HDAC overexpression and BDNF-associated Akt/GSK-3beta signaling.
    Read more
  • LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol Int
    Read more
  • miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Liu J et al., 2017 Nov, Oncol Lett
    Read more
  • Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity. Leibinger M et al., 2017 Jul 3, Proc Natl Acad Sci U S A
    Read more