GSK3987

MedChem Express

GSK3987 [264206-85-1]

10

264206-85-1

Research Use Only

99.19

C24H20N2O3

384.43

GSK3987 is a pan LXRalpha/beta agonist with EC50s of 50 nM, 40 nM for LXRalpha-SRC1 and LXRbeta-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation[1].

O=C(N(C1=O)CC2=CC=CC=C2)C(NC3=CC=C(C=C3)OC)=C1C4=CC=CC=C4

-20°C

12352200