GSK467

MedChem Express

GSK467 [1628332-52-4]

10

1628332-52-4

Research Use Only

99.55

C17H13N5O2

319.32

GSK467 is a cell penetrant and selective KDM5B (JARID1B or PLU1) inhibitor with a K i of 10 nM and an IC 50 of 26 nM. GSK467 shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members [1] [2] .

O=C1C2=C(NC(OC3=CN(N=C3)CC4=CC=CC=C4)=N1)C=NC=C2

-20°C,2°C to 8°C

12352200