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GSK481

M5209
AbMole BioScience
CAS Number1622849-58-4
DownloadDatasheet
Product group Chemicals
Estimated Purity0.999
Molecular Weight377.39
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    GSK481
  • Delivery Days Customer
    9
  • CAS Number
    1622849-58-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.999
  • Molecular Formula
    C21H19N3O4
  • Molecular Weight
    377.39
  • Scientific Description
    GSK481 is a highly effective, selective and specific RIPK1 inhibitor with an IC50 value of 1.3 nM, which can inhibit the phosphorylation of Ser166 in wild-type human RIPK1 (IC50 value of 2.8 nM). The IC50 value of GSK481 against U937 cells was 10 nM.
  • SMILES
    CN1C(=O)C(COC2=CC=CC=C12)NC(=O)C3=NOC(=C3)CC4=CC=CC=C4
  • UNSPSC
    12352200