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GSK547 [2226735-55-1]

GSK547 [2226735-55-1]

T7397
TargetMol Chemicals
CAS Number2226735-55-1
Product group Chemicals
Molecular Weight396.39
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GSK547 [2226735-55-1]
  • Delivery Days Customer
    9
  • CAS Number
    2226735-55-1
  • Certification
    Research Use Only
  • Chemical Name
    GSK547
  • Molecular Formula
    C20H18F2N6O
  • Molecular Weight
    396.39
  • Scientific Description
    GSK547 (GSK547) is a highly selective and potent RIP1 kinase inhibitor that disrupts macrophage-mediated adaptive immune tolerance in pancreatic cancer.
  • Shelf life instruction
    3 years
  • SMILES
    Fc1cc(F)cc(c1)[C@@H]1CC=NN1C(=O)C1CCN(CC1)c1cc(ncn1)C#N
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Wang W, Marinis JM, Beal AM, et al. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 2018,34(5):757-774.e7. doi: 10.1016/j.ccell.2018.10.006
    Read this paper

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