GSK620

MedChem Express

GSK620 [2088410-46-0]

10

2088410-46-0

Research Use Only

99.79

C18H19N3O3

325.36

GSK620 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood[1].

O=C(C1=CC(C(NC2CC2)=O)=CN(CC3=CC=CC=C3)C1=O)NC

-20°C,2°C to 8°C

12352200