GSK717

MedChem Express

GSK717 [1595278-21-9]

9

1595278-21-9

Research Use Only

99.88

C28H28N4O2

452.55

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC 50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells [1] .

O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O

-20°C,2°C to 8°C

12352200