GSTZ1 antibody [N1C3]
GTX106109
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetGSTZ1
Overview
- SupplierGeneTex
- Product NameGSTZ1 antibody [N1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.98 mg/ml
- ConjugateUnconjugated
- Gene ID2954
- Target nameGSTZ1
- Target descriptionglutathione S-transferase zeta 1
- Target synonymsglutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione transferase zeta 1; GSTZ1-1; MAAI; MAAID; MAI; maleylacetoacetate isomerase; maleylacetone isomerase; S-(hydroxyalkyl)glutathione lyase
- HostRabbit
- IsotypeIgG
- Protein IDO43708
- Protein NameMaleylacetoacetate isomerase
- Scientific DescriptionThis gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis. Wang Q et al., 2021 Apr 30, Cell Death DisRead more
- GSTZ1-1 downregulates Wnt/beta-catenin signalling in hepatocellular carcinoma cells. Lei C et al., 2020 Jan, FEBS Open BioRead more
- GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. Li J et al., 2019 Oct 30, J Exp Clin Cancer ResRead more