GTS-21 [148372-04-7]

MedChem Express

GTS-21 [148372-04-7]

5

148372-04-7

Research Use Only

C19H20N2O2

308.37

GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (alpha7-nAChR) agonist with anti inflammatory and cognition enhancing activities. GTS-21 dihydrochloride is also a alpha4beta2 (Ki=20 nM for humanalpha4beta2) and 5-HT3A receptor (IC50=3.1 microM) antagonist. GTS-21 can be used in age-associated memory impairment (AAMI) and Alzheimers disease research[1][2][3].

COC(C=C(C=C1)OC)=C1/C=C2C(C3=CN=CC=C3)=NCCC/2

12352200