GTS-21 (dihydrochloride)

MedChem Express

GTS-21 (dihydrochloride) [156223-05-1]

10

156223-05-1

Research Use Only

99.92

C19H22Cl2N2O2

381.30

GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (alpha7-nAChR) agonist with anti inflammatory and cognition enhancing activities. GTS-21 dihydrochloride is also a alpha4beta2 (Ki=20 nM for humanalpha4beta2) and 5-HT3A receptor (IC50=3.1 microM) antagonist[1][2].

COC1=CC(OC)=CC=C1/C=C2CCCN=C\2C3=CC=CN=C3.Cl[H].Cl[H]

2°C to 8°C

12352200