Guanosine 5-diphosphate (disodium salt) [7415-69-2]

MedChem Express

Guanosine 5-diphosphate (disodium salt) [7415-69-2]

9

7415-69-2

Research Use Only

99.0

C10H13N5Na2O11P2

487.16

Guanosine 5-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5-diphosphate disodium salt activates adenosine 5-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI)[1][2][3][4][5].

O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(O)([O-])=O)([O-])=O.[2Na+]

-20°C

41106300