Gusacitinib (hydrochloride)
HY-103018A
CAS Number2228989-14-6
Product group Chemicals
Molecular Weight496.99
Overview
- SupplierMedChem Express
- Product NameGusacitinib (hydrochloride)
- Delivery Days Customer10
- CAS Number2228989-14-6
- CertificationResearch Use Only
- Molecular FormulaC24H29ClN8O2
- Molecular Weight496.99
- Scientific DescriptionGusacitinib (ASN-002) hydrochloride is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib hydrochloride rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib hydrochloride can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma[1][2].
- SMILESN#CCC1CCN(C2=NC(NC3=CC=C(N4CCC(O)CC4)C=C3)=C5C(C=NNC5=O)=N2)CC1.[H]Cl
- UNSPSC12352200