GV-58

MedChem Express

GV-58 [1402821-41-3]

10

1402821-41-3

Research Use Only

99.22

C18H26N6OS

374.50

GV-58 is a novel N- and P/Q-type calcium ( Ca 2+ ) channel agonist with EC 50 s of 7.21 and 8.81 microM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca 2+ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research [1] [2] [3] .

CC[C@@H](NC1=NC(NCC2=CC=C(C)S2)=C3N=CN(CCC)C3=N1)CO

-20°C,2°C to 8°C

12352200