GW 590735 (sodium) [343322-50-9]

MedChem Express

GW 590735 (sodium) [343322-50-9]

9

343322-50-9

Research Use Only

C23H20F3N2NaO4S

500.47

GW 590735 sodium is a potent and selective PPARalpha agonist with activity in regulating lipid metabolism. GW 590735 significantly increased high-density lipoprotein (HDL) cholesterol, decreased low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) cholesterol, and significantly reduced triglycerides. The maximum increases in HDL cholesterol for GW 590735 were 37%, 53% and 84%, respectively, compared with bezafibrate, torcetrapib and GW 590735[1].

O=C(C(C)(C)OC1=CC=C(CNC(C2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=O)C=C1)O[Na]

12352200