GW-870086

MedChem Express

GW-870086 [827319-43-7]

10

827319-43-7

Research Use Only

99.59

C31H39F2NO6

559.64

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC 50 of 10.1 in A549 cells expressing NF-kappaB.

O=C(C1C(C)(C)C1(C)C)O[C@]2([C@@]3([C@@]([C@@]4([H])[C@@](F)([C@@]5(C([C@@H](F)C4)=CC(C=C5)=O)C)[C@@H](O)C3)([H])C[C@H]2C)C)C(OCC#N)=O

-20°C,2°C to 8°C

12352200