GW274150 (phosphate) [438542-15-5]

MedChem Express

GW274150 (phosphate) [438542-15-5]

9

438542-15-5

Research Use Only

98.15

C8H20N3O6PS

317.30

GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 microM; Kd=40 nM) and rat iNOS (ED50=1.15 microM). GW274150 phosphate displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation[1][2].

CC(NCCSCC[C@H](N)C(O)=O)=N.O=P(O)(O)O

2°C to 8°C

12352200