GW583340 (dihydrochloride) [1173023-85-2]
HY-103439
Overview
- SupplierMedChem Express
- Product NameGW583340 (dihydrochloride) [1173023-85-2]
- Delivery Days Customer5
- CAS Number1173023-85-2
- CertificationResearch Use Only
- Molecular FormulaC28H27Cl3FN5O3S2
- Molecular Weight671.03
- Scientific DescriptionGW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50: 0.01 and 0.014 microM respectively). GW 583340 dihydrochloride reverses ABCG2- and ABCB1-mediated drug resistance. GW 583340 dihydrochloride has anti-cancer activity[1][2][3].
- SMILESO=S(CCNCC1=NC(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)=CS1)(C)=O.Cl.Cl
- Storage InstructionRT
- UNSPSC12352200