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GW583340 (dihydrochloride) [1173023-85-2]

Research Use Only
HY-103439
MedChem Express
CAS Number1173023-85-2
Product group Chemicals
Molecular Weight671.03
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GW583340 (dihydrochloride) [1173023-85-2]
  • Delivery Days Customer
    5
  • CAS Number
    1173023-85-2
  • Certification
    Research Use Only
  • Molecular Formula
    C28H27Cl3FN5O3S2
  • Molecular Weight
    671.03
  • Scientific Description
    GW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50: 0.01 and 0.014 microM respectively). GW 583340 dihydrochloride reverses ABCG2- and ABCB1-mediated drug resistance. GW 583340 dihydrochloride has anti-cancer activity[1][2][3].
  • SMILES
    O=S(CCNCC1=NC(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)=CS1)(C)=O.Cl.Cl
  • Storage Instruction
    RT
  • UNSPSC
    12352200