GYY 4137

AdipoGen Life Sciences

GYY 4137

10

106740-09-4

Research Use Only

>95%

C11H16NO2PS2 . C4H9NO

288.4 . 87.1

Chemical. CAS: 106740-09-4. Formula: C11H16NO2PS2 . C4H9NO. MW: 288.4 . 87.1. Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. - Water-soluble, slow-releasing hydrogen sulfide (H2S) donor [1]. Exhibits vasodilator and antihypertensive activity [1, 2, 4]. Anti-inflammatory [2, 3]. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways [2, 3]. Causes stomatal opening and reduces nitric oxide accumulation in plants [5]. Oxidative stress-induced cell death inhibitor [6]. Shows novel anti-cancer effects in vitro and in vivo [7]. Anti-thrombotic via p-selectin dependent mechanism [8].

C1COCC[NH2+]1.COC1=CC=C(C=C1)P([S-])(=S)N1CCOCC1

-20°C,2°C to 8°C

12352200