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H-151 [941987-60-6]
T5674
Overview
- SupplierTargetMol Chemicals
- Product NameH-151 [941987-60-6]
- Delivery Days Customer9
- CAS Number941987-60-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameH-151
- Molecular FormulaC17H17N3O
- Molecular Weight279.34
- Scientific DescriptionH-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammatory diseases in vivo and ex vivo.
- Shelf life instruction3 years
- SMILESCCc1ccc(NC(=O)Nc2c[nH]c3ccccc23)cc1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Kobritz M, et al. H151, A SMALL MOLECULE INHIBITOR OF STING AS A NOVEL THERAPEUTIC IN INTESTINAL ISCHEMIA-REPERFUSION INJURY. Shock. 2022 Sep 1;58(3):241-250.Read more