H-89 . dihydrochloride [127243-85-0]

AdipoGen Life Sciences

H-89 . dihydrochloride

10

127243-85-0

Research Use Only

>98%

C20H20BrN3O2S . 2HCl

446.4 . 72.9

Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor [1-3]. Protein kinase Cmicro (PKCmicro) inhibitor [4]. Ca2+/calmodulin-dependent protein kinase II inhibitor [2]. Casein kinase I inhibitor [2]. Myosin light chain kinase (MLCK) inhibitor [2]. Apoptosis enhancer [5]. Tool to study protein crystal structure-inhibitor interactions [6]. Rho kinase inhibitor [7]. Cell proliferation inhibitor [8]. Review [9]. - Chemical. CAS: 130964-39-5 - 127243-85-0 (free base). Formula: C20H20BrN3O2S . 2HCl. MW: 446.4 . 72.9. Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Protein kinase Cmicro (PKCmicro) inhibitor. Ca2+/calmodulin-dependent protein kinase II inhibitor. Casein kinase I inhibitor. Myosin light chain kinase (MLCK) inhibitor. Apoptosis enhancer. Tool to study protein crystal structure-inhibitor interactions. Rho kinase inhibitor. Cell proliferation inhibitor. Review.

BrC1=CC=C(C=CCNCCNS(=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1

2°C to 8°C

12352200