H-Ras deltaC (S17N), Harvey rat sarcoma viral oncogene homolog, residues 1-166, human, recombinant, E. coli

Jena Bioscience

H-Ras deltaC (S17N), Harvey rat sarcoma viral oncogene homolog, residues 1-166, human, recombinant, E. coli

5

Research Use Only

Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). H-Ras deltaC (aa 1 - 171) lacks the C-terminus with the CaaX recognition sequence necessary for anchoring Ras into the plasma membrane. The mutation S17N results in a 40-fold increase in the affinity for GTP without affecting its affinity for GDP. Protein preparation is 95% GDP- and 5% GTP-loaded, measured by HPLC.

-80°C

41116133