H-Ras (G12V)GST, Harvey rat sarcoma viral oncogene homolog, human, recombinant, E. coli

Jena Bioscience

H-Ras (G12V)GST, Harvey rat sarcoma viral oncogene homolog, human, recombinant, E. coli

5

Research Use Only

Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase. The GST-Tag facilitates the proteins application in typical GST pull-down assays.

-80°C

41116133