H3B-6527

MedChem Express

H3B-6527 [1702259-66-2]

14

1702259-66-2

98.0

C29H34Cl2N8O4

629.54

H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC 50 of IC 50 s of 320 nM, 1290 nM and 1060 nM respectively. H3B-6527 has potent anti-cancer activity [1] .

C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O

-20°C,2°C to 8°C

12352200