H3R antagonist 2
HY-146383
Molecular Weight379.49
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameH3R antagonist 2 [2970985-05-6]
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC24H29NO3
- Molecular Weight379.49
- Scientific DescriptionH3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor (H3R) antagonist with a Ki of 170 nM for hH3R . H3R antagonist 2 shows inhibitory effects with IC50 values of 180, 880 and 775 nM for acetylcholinesterase, butyrylcholinesterase and human monoamine oxidase B (hMAO B), respectively. H3R antagonist 2 shows favorable anti-neuropathic pain and memory-enhancing effects. H3R can across BBB[1].
- SMILESO=C1C2=CC(OCCCCCN3CCCCCC3)=CC=C2OC4=C1C=CC=C4
- UNSPSC12131703