HA14-1 [65673-63-4]

MedChem Express

HA14-1 [65673-63-4]

10

65673-63-4

Research Use Only

98.0

C17H17BrN2O5

409.23

HA14-1 is a Bcl-2/Bcl-XL antagonist. HA14-1 binds the designated pocket on Bcl-2 with the IC50 of ~9 microM in competing with the Bcl-2 binding of Flu-BakBH3, and inhibits its function.

CCOC(C1=C(N)OC2=CC=C(Br)C=C2[C@@]1([H])[C@H](C#N)C(OCC)=O)=O

-20°C,2°C to 8°C

12352200