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ProductsBack/hA2A/hCA XII modulator 1 [2548963-55-7]

hA2A/hCA XII modulator 1 [2548963-55-7]

HY-146979
MedChem Express
CAS Number2548963-55-7
DownloadMSDS
Product group Chemicals
Molecular Weight501.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    hA2A/hCA XII modulator 1 [2548963-55-7]
  • Delivery Days Customer
    10
  • CAS Number
    2548963-55-7
  • Certification
    Research Use Only
  • Molecular Formula
    C24H19N7O4S
  • Molecular Weight
    501.52
  • Scientific Description
    hA2A/hCA XII modulator 1 (compound 14), a triazolopirazine, is a potent hA2A adenosine receptor (hA2AAR) antagonist with Kis of 6.4 nM, 4.819 microM, >30 microM for hA2AAR, hA1AR, hA3AR, respectively. hA2A/hCA XII modulator 1 is a potent human carbonic anhydrase XII (hCA XII) inhibitor with Kis of 6.2 nM, 46 nM, 466 nM, 8.351 microM for hCA XII, hCA II, hCA IX and hCA I, respectively. hA2A/hCA XII modulator 1 has the potential for cancer research[1].
  • SMILES
    O=C(NC1=CC=C(C2=CN3C(C(N)=N2)=NN(C4=CC=CC=C4)C3=O)C=C1)C5=CC=C(S(=O)(N)=O)C=C5
  • UNSPSC
    12131703