HAA-09 [1422051-33-9]

MedChem Express

HAA-09 [1422051-33-9]

10

1422051-33-9

Research Use Only

C17H18F2N6O2

376.36

HAA-09 is an orally active and potent anti-influenza agent, targeting the influenza PB2_cap binding domain. HAA-09 displays potent anti-influenza A virus activity, with an EC50 of 0.03 microM. HAA-09 shows polymerase inhibition, with an IC50 of 0.06+/-0.004 microM. HAA-09 blocks virus replication without causing obvious cytotoxicity[1].

CC(C)(N(NC1=C(C=NC(C2=CNC3=C2C=C(C=N3)F)=N1)F)CC(O)=O)C

12131703