hAChE/hBACE-1-IN-2
HY-149288
Molecular Weight408.52
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamehAChE/hBACE-1-IN-2
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC22H24N4O2S
- Molecular Weight408.52
- Scientific DescriptionhAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 microM, 1.48 microM and 0.38 microM, respectively. hAChE/hBACE-1-IN-2 has antioxidant activity. hAChE/hBACE-1-IN-2 also inhibits Abeta11-42 aggregation. hAChE/hBACE-1-IN-2 can be used to study Alzheimers disease[1].
- SMILESO=C(CSC1=NN=C(C2=CC=CC=C2)O1)NC3CCN(CC3)CC4=CC=CC=C4
- UNSPSC12131703