hAChE/hBACE-1-IN-2

MedChem Express

hAChE/hBACE-1-IN-2

14

Research Use Only

C22H24N4O2S

408.52

hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 microM, 1.48 microM and 0.38 microM, respectively. hAChE/hBACE-1-IN-2 has antioxidant activity. hAChE/hBACE-1-IN-2 also inhibits Abeta11-42 aggregation. hAChE/hBACE-1-IN-2 can be used to study Alzheimers disease[1].

O=C(CSC1=NN=C(C2=CC=CC=C2)O1)NC3CCN(CC3)CC4=CC=CC=C4

12131703