Hairless antibody

GeneTex

Hairless antibody

9

WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

HR

HR lysine demethylase and nuclear receptor corepressor

[histone H3]-dimethyl-L-lysine(9) demethylase hairless; ALUNC; AU; hair growth associated; hairless homolog; HSA277165; HYPT4; lysine-specific demethylase hairless; MUHH; MUHH1; protein hairless

Rabbit

IgG

Lysine-specific demethylase hairless

This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203