Bio-Connect

HAKAI antibody

Research Use Only
ORB67187
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCBLL1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    HAKAI antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:500-1:1000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID79872
  • Target name
    CBLL1
  • Target description
    Cbl proto-oncogene like 1
  • Target synonyms
    Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; casitas B-lineage lymphoma-transforming sequence-like protein 1; Cbl proto-oncogene like 1, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; c-Cbl-like protein 1; E3 ubiquitin-protein ligase Hakai; E-cadherin binding protein E7; HAKAI; RING finger protein 188; RING-type E3 ubiquitin transferase Hakai; RNF188
  • Host
    Rabbit
  • Protein IDQ75N03
  • Protein Name
    E3 ubiquitin-protein ligase Hakai
  • Scientific Description
    Rabbit polyclonal to HAKAI.HAKAI is also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1),which is an E3 ubiquitin-protein ligase for the E-cadherin (CDH1) complex and mediates itsubiquitination, endocytosis, and degradation in the lysosomes. CDH1 is endocytosed as aconsequence of tyrosine phosphorylation and ubiquitination. HAKAI interacts with tyrosinephosphorylatedCDH1 and mediates this process. HAKAI contains a RING-finger domain and is alsothought to have a role in the control of cell proliferation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203