HAKAI antibody
ORB67187
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCBLL1
Overview
- SupplierBiorbyt
- Product NameHAKAI antibody
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:500-1:1000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79872
- Target nameCBLL1
- Target descriptionCbl proto-oncogene like 1
- Target synonymsCas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; casitas B-lineage lymphoma-transforming sequence-like protein 1; Cbl proto-oncogene like 1, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; c-Cbl-like protein 1; E3 ubiquitin-protein ligase Hakai; E-cadherin binding protein E7; HAKAI; RING finger protein 188; RING-type E3 ubiquitin transferase Hakai; RNF188
- HostRabbit
- Protein IDQ75N03
- Protein NameE3 ubiquitin-protein ligase Hakai
- Scientific DescriptionRabbit polyclonal to HAKAI.HAKAI is also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1),which is an E3 ubiquitin-protein ligase for the E-cadherin (CDH1) complex and mediates itsubiquitination, endocytosis, and degradation in the lysosomes. CDH1 is endocytosed as aconsequence of tyrosine phosphorylation and ubiquitination. HAKAI interacts with tyrosinephosphorylatedCDH1 and mediates this process. HAKAI contains a RING-finger domain and is alsothought to have a role in the control of cell proliferation.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203