Halofuginone hydrobromide [64924-67-0]
T3524
CAS Number64924-67-0
Product group Chemicals
Estimated Purity98.50%
Molecular Weight495.59
Overview
- SupplierTargetMol Chemicals
- Product NameHalofuginone hydrobromide [64924-67-0]
- Delivery Days Customer9
- CAS Number64924-67-0
- CertificationResearch Use Only
- Chemical NameHalofuginone hydrobromide
- Estimated Purity98.50%
- Molecular FormulaC16H17BrClN3O3.HBr
- Molecular Weight495.59
- Scientific DescriptionHalofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases.
- Shelf life instruction3 years
- SMILESBr.O[C@H]1CCCN[C@@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O
- Storage Instruction-20°C
- UNSPSC12352200
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