HAT-SIL-TG-1&AT
HY-149257
Overview
- SupplierMedChem Express
- Product NameHAT-SIL-TG-1&AT [2973282-50-5]
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC60H69N17O11S
- Molecular Weight1236.36
- Scientific DescriptionHAT-SIL-TG-1&AT is a Janus tyrosine kinase (JAK) inhibitor with antitumor effects. HAT-SIL-TG-1&AT is the hypoxia-activated prodrug, witch inhibits JAK-STAT signaling in tumor tissue. And HAT-SIL-TG-1&AT inhibits HEL cells proliferation and downregulated phosphorylated STAT3/5 under hypoxic conditions[1].
- SMILESCC1=CC(COC(N2C=C(C(C3=NC4=C(N3)C=CC(CN5CCOCC5)=C4)=N2)NC(NC6CC6)=O)=O)=C(C(COC(N7CCN(CC7)C8=CC=C(C=C8)NC9=NC=C(C(NC%10=CC(S(=O)(NC(C)(C)C)=O)=CC=C%10)=N9)C)=O)=C1)OCC%11=CN=C(N%11C)[N+]([O-])=O
- UNSPSC12131703