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HAUS2 antibody [N1C3-2]

Name: HAUS2 antibody [N1C3-2]
SKU: GTX118734_G10
Availability: BackOrder

GTX118734

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Product group Antibodies

TargetHAUS2

Overview

Supplier
GeneTex
Product Name
HAUS2 antibody [N1C3-2]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID55142
Target name
HAUS2
Target description
HAUS augmin like complex subunit 2
Target synonyms
C15orf25, CEP27, HsT17025, HAUS augmin-like complex subunit 2, centrosomal protein 27kDa, centrosomal protein of 27 kDa
Host
Rabbit
Isotype
IgG
Protein IDQ9NVX0
Protein Name
HAUS augmin-like complex subunit 2
Scientific Description
HAUS2 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Ustinova K, Ruhnow F, Gili M, et al. Microtubule binding of the human augmin complex is directly controlled by importins and Ran-GTP. J Cell Sci. 2023,136(12). doi: 10.1242/jcs.261096
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Tsai CY, Ngo B, Tapadia A, et al. Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly. J Biol Chem. 2011,286(34):30097-106. doi: 10.1074/jbc.M111.266767
Read this paper