WB analysis of human brain tissue lysate using GTX84984 Hax1a antibody [8F9G7]. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of human brain tissue lysate using GTX84984 Hax1a antibody [8F9G7]. Working concentration : (A) 1 and (B) 2 microg/ml
Hax1a antibody [8F9G7]
GTX84984
Overview
- SupplierGeneTex
- Product NameHax1a antibody [8F9G7]
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Clone ID8F9G7
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID10456
- Target nameHAX1
- Target descriptionHCLS1 associated protein X-1
- Target synonymsHAX-1; HCLS1 (and PKD2) associated protein; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; SCN3
- Protein IDO00165
- Protein NameHCLS1-associated protein X-1
- Scientific DescriptionThe HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203