hBChE-IN-1 [1776948-12-9]
HY-149273
CAS Number1776948-12-9
Product group Chemicals
Molecular Weight466.70
Overview
- SupplierMedChem Express
- Product NamehBChE-IN-1 [1776948-12-9]
- Delivery Days Customer10
- CAS Number1776948-12-9
- CertificationResearch Use Only
- Molecular FormulaC27H34N2OS2
- Molecular Weight466.70
- Scientific DescriptionhBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC50=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against tau and Abeta40 protein aggregation, with IC50 values of 20 and 4.3 microM, respectively. hBChE-IN-1 can be used for Alzheimers disease research[1].
- SMILES[H][C@]12CCCCN1CCC[C@H]2CSCCCNC3=CC=C(C4=C3C(C5=CC=CC=C5S4)=O)C
- UNSPSC12131703