HBG1/HBG2 Polyclonal Antibody

Reddot Biotech

HBG1/HBG2 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

HBG1

hemoglobin subunit gamma 1

A-gamma globin; gamma A hemoglobin; gamma globin; gamma-1-globin; hb F Agamma; HBGA; HBGR; HBG-T2; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin subunit gamma-1; hemoglobin, gamma A; hemoglobin, gamma, regulator of; HSGGL1; PRO2979

Rabbit

IgG

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5-epsilon -- gamma-G -- gamma-A -- delta -- beta--3.

Human

-20°C

12352203