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HBT1

HY-122742
MedChem Express
CAS Number489408-02-8
Product group Chemicals
Estimated Purity99.83
Molecular Weight386.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    HBT1 [489408-02-8]
  • Delivery Days Customer
    10
  • CAS Number
    489408-02-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C16H17F3N4O2S
  • Molecular Weight
    386.39
  • Scientific Description
    HBT1 is a potent alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor (AMPA-R) potentiator. HBT1 bonds with S518 in the ligand-binding domain (LBD) of AMPA-R in a glutamate-dependent manner. HBT1 did not show remarkable bell-shaped response in brain-derived neurotrophic factor (BDNF) production in primary neurons[1].
  • SMILES
    O=C(NC1=C(C(N)=O)C(CCCC2)=C2S1)CN3N=C(C(F)(F)F)C=C3C
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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