HBT1 [489408-02-8]
HY-122742
Overview
- SupplierMedChem Express
- Product NameHBT1 [489408-02-8]
- Delivery Days Customer10
- CAS Number489408-02-8
- CertificationResearch Use Only
- Estimated Purity99.83
- Molecular FormulaC16H17F3N4O2S
- Molecular Weight386.39
- Scientific DescriptionHBT1 is an effective AMPA receptor AMPA-R potentiator. HBT1 specifically binds to the ligand-binding domain (LBD) of AMPAR and enhances receptor activity only when AMPA is present., HBT1 has almost no agonistic effect (i.e., reaching the optimal concentration, and then the efficacy decreases as the concentration continues to increase) compared with traditional AMPA-R potentiator, avoiding the bell-shaped reaction of brain-derived neurotrophic factor (BDNF) production in primary neurons. HBT1 can be applicable to a wider range of neurological and psychiatric diseases (such as depression, Alzheimers disease, etc.)[1].
- SMILESO=C(NC1=C(C(N)=O)C(CCCC2)=C2S1)CN3N=C(C(F)(F)F)C=C3C
- Storage Instruction2°C to 8°C
- UNSPSC12131703