HBV-IN-25 [2161364-69-6]

MedChem Express

HBV-IN-25 [2161364-69-6]

10

2161364-69-6

Research Use Only

C18H14ClNO4

343.76

HBV-IN-25 is a good potency, orally active novel HBV cccDNA reducer. HBV-IN-25 has anti-HBeAg potency and anti-HBV activity with IC50 values of 0.58 microM and 1.15 microM, respectively. HBV-IN-25 has good aqueous solubility (LYSA>452 microg/mL) and good PK property with no cellular toxicity[1].

O=C([C@H]1CN(C2=CC(OC3=C4C=CC=C3Cl)=C(C=C2)C4=O)CC1)O

12131703