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HC Toxin [83209-65-8]

HC Toxin [83209-65-8]

T35774
TargetMol Chemicals
CAS Number83209-65-8
Product group Chemicals
Molecular Weight436.509
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HC Toxin [83209-65-8]
  • Delivery Days Customer
    44
  • CAS Number
    83209-65-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    HC Toxin
  • Molecular Formula
    C21H32N4O6
  • Molecular Weight
    436.509
  • Scientific Description
    HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.
  • Shelf life instruction
    3 years
  • SMILES
    C[C@H]1NC(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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