hCAI/II-IN-5 [2428389-67-5]

MedChem Express

hCAI/II-IN-5 [2428389-67-5]

10

2428389-67-5

Research Use Only

C21H18Cl2N8O4S2

581.45

hCAI/II-IN-5 (compound MZ8) is a potent hCA I and hCA II (human carbonic anhydrase isoenzymes I and II) inhibitor, with IC50 values of 37.88 and 45.23 nM, respectively. hCAI/II-IN-5 also shows inhibition profile against alpha-Glycosidase and AChE, with IC50 values of 48.98 and 420.14 nM, respectively. hCAI/II-IN-5 can be used for the research of many diseases such as diabetes, Alzheimers disease, heart failure, ulcer, and epilepsy[1].

ClC1=CC=C(NC2=NC(NC3=CC=C(S(=O)(N)=O)C=C3)=NC(NC4=CC=C(S(=O)(N)=O)C=C4)=N2)C=C1Cl

12131703