hCAIX-IN-10 [2497504-72-8]
HY-147827
CAS Number2497504-72-8
Product group Chemicals
Molecular Weight479.55
Overview
- SupplierMedChem Express
- Product NamehCAIX-IN-10 [2497504-72-8]
- Delivery Days Customer10
- CAS Number2497504-72-8
- CertificationResearch Use Only
- Molecular FormulaC28H21N3O3S
- Molecular Weight479.55
- Scientific DescriptionhCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells[1].
- SMILESO=C1N(C2=CC=CC(C)=C2)C(C3=CN(C4=CC=CC=C4)N=C3C5=CC6=CC=CC=C6OC5=O)SC1
- UNSPSC12131703