Bio-Connect

hCAIX-IN-11 [2497504-81-9]

HY-147828
MedChem Express
CAS Number2497504-81-9
Product group Chemicals
Molecular Weight406.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    hCAIX-IN-11 [2497504-81-9]
  • Delivery Days Customer
    10
  • CAS Number
    2497504-81-9
  • Certification
    Research Use Only
  • Molecular Formula
    C21H15ClN4O3
  • Molecular Weight
    406.82
  • Scientific Description
    hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells[1].
  • SMILES
    N#CC1=CC=C(CN2N=NC(COC3=CC=C(C(O4)=C3)C(CCl)=CC4=O)=C2)C=C1
  • UNSPSC
    12131703