hCAIX-IN-11 [2497504-81-9]
HY-147828
Overview
- SupplierMedChem Express
- Product NamehCAIX-IN-11 [2497504-81-9]
- Delivery Days Customer10
- CAS Number2497504-81-9
- CertificationResearch Use Only
- Molecular FormulaC21H15ClN4O3
- Molecular Weight406.82
- Scientific DescriptionhCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells[1].
- SMILESN#CC1=CC=C(CN2N=NC(COC3=CC=C(C(O4)=C3)C(CCl)=CC4=O)=C2)C=C1
- UNSPSC12131703