hCAIX-IN-12 [2414598-85-7]

MedChem Express

hCAIX-IN-12 [2414598-85-7]

10

2414598-85-7

Research Use Only

C18H14N4O3S2

398.46

hCAIX-IN-12 is a potent hCAIX inhibitor with IC50 values of 0.74, 10.78 microM for CAIX and CAII, respectively. hCAIX-IN-12 shows antiproliferative effect and induces apoptosis. hCAIX-IN-12 increases ROS production. hCAIX-IN-12 has the potential for the research of colorectal cancer (CRC) [1].

O=S(C1=CC=C(N)C=C1)(NC2=C(C3=NC(C4=CC=CC=C4)=NO3)SC=C2)=O

12131703