hCAIX-IN-8 [2414633-40-0]
HY-147722
Overview
- SupplierMedChem Express
- Product NamehCAIX-IN-8 [2414633-40-0]
- Delivery Days Customer10
- CAS Number2414633-40-0
- CertificationResearch Use Only
- Molecular FormulaC19H16N4O6
- Molecular Weight396.35
- Scientific DescriptionhCAIX-IN-8 (compound 7i) is a potent and selective hCAIX inhibitor with IC50s of 1.99, 0.024, 1.10 microM for CAII, CAIX, CAVA respectively. hCAIX-IN-8 shows anti-proliferation activity with low toxicity. hCAIX-IN-8 decreases the epithelial to mesenchymal transitions and induces apoptosis. hCAIX-IN-8 inhibits cell migration and colonization potential[1].
- SMILESCOC1=CC(/C=C/C(O)=O)=CC=C1OCC2=CN(N=N2)C3=CC([N+]([O-])=O)=CC=C3
- UNSPSC12131703