Bio-Connect

hCAIX-IN-8 [2414633-40-0]

HY-147722
MedChem Express
CAS Number2414633-40-0
Product group Chemicals
Molecular Weight396.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    hCAIX-IN-8 [2414633-40-0]
  • Delivery Days Customer
    10
  • CAS Number
    2414633-40-0
  • Certification
    Research Use Only
  • Molecular Formula
    C19H16N4O6
  • Molecular Weight
    396.35
  • Scientific Description
    hCAIX-IN-8 (compound 7i) is a potent and selective hCAIX inhibitor with IC50s of 1.99, 0.024, 1.10 microM for CAII, CAIX, CAVA respectively. hCAIX-IN-8 shows anti-proliferation activity with low toxicity. hCAIX-IN-8 decreases the epithelial to mesenchymal transitions and induces apoptosis. hCAIX-IN-8 inhibits cell migration and colonization potential[1].
  • SMILES
    COC1=CC(/C=C/C(O)=O)=CC=C1OCC2=CN(N=N2)C3=CC([N+]([O-])=O)=CC=C3
  • UNSPSC
    12131703