HDAC-IN-39 [2414046-33-4]

MedChem Express

HDAC-IN-39 [2414046-33-4]

10

2414046-33-4

Research Use Only

C27H26N4O4S

502.58

HDAC-IN-39 (compound 16c) is a potent HDAC inhibitor, with IC50 values of 1.07 microM (HDAC1), 1.47 microM (HDAC2), and 2.27 microM (HDAC3), respectively. HDAC-IN-39 also significantly inhibits microtubule polymerization. HDAC-IN-39 induces cell cycle arrest at the G2/M phase. HDAC-IN-39 displays promising anticancer activity against resistant cancer cells[1].

COC1=CC=C(C=C1)S(=O)(NC2=CC=CC=C2NCC3=CC=C(C=C3)C(NC4=CC=CC=C4N)=O)=O

12131703