HDAC-IN-63 [2920046-95-1]
HY-149474
CAS Number2920046-95-1
Product group Chemicals
Molecular Weight529.42
Overview
- SupplierMedChem Express
- Product NameHDAC-IN-63 [2920046-95-1]
- Delivery Days Customer14
- CAS Number2920046-95-1
- CertificationResearch Use Only
- Molecular FormulaC25H26Cl2N6O3
- Molecular Weight529.42
- Scientific DescriptionHDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor (IC50: 0.844 and 30.0 nM for FLT3 and HDAC1 respectively). HDAC-IN-63 inhibits MV4-11 cell proliferation (IC50: 92 nM. HDAC-IN-63 induces apoptosis and arrests cell cycle in MV4-11 cells. HDAC-IN-63 can be used for research of acute myeloid leukemia (AML)[1].
- SMILESClC1=CC=CC(Cl)=C1CN(C=N2)C3=C2C=CC(C4=CC(NC(CCCCCCC(NO)=O)=O)=NN4)=C3
- UNSPSC12131703