Bio-Connect

HDAC-IN-63 [2920046-95-1]

HY-149474
MedChem Express
CAS Number2920046-95-1
Product group Chemicals
Molecular Weight529.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    HDAC-IN-63 [2920046-95-1]
  • Delivery Days Customer
    14
  • CAS Number
    2920046-95-1
  • Certification
    Research Use Only
  • Molecular Formula
    C25H26Cl2N6O3
  • Molecular Weight
    529.42
  • Scientific Description
    HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor (IC50: 0.844 and 30.0 nM for FLT3 and HDAC1 respectively). HDAC-IN-63 inhibits MV4-11 cell proliferation (IC50: 92 nM. HDAC-IN-63 induces apoptosis and arrests cell cycle in MV4-11 cells. HDAC-IN-63 can be used for research of acute myeloid leukemia (AML)[1].
  • SMILES
    ClC1=CC=CC(Cl)=C1CN(C=N2)C3=C2C=CC(C4=CC(NC(CCCCCCC(NO)=O)=O)=NN4)=C3
  • UNSPSC
    12131703