More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/HDAC4 antibody [N3C1], Internal

HDAC4 antibody [N3C1], Internal

GTX110231
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHDAC4
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC4 antibody [N3C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9759
  • Target name
    HDAC4
  • Target description
    histone deacetylase 4
  • Target synonyms
    AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, NEDCHF, NEDCHID, histone deacetylase 4, histone deacetylase A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP56524
  • Protein Name
    Histone deacetylase 4
  • Scientific Description
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Zhao B, Fu J, Ni H, et al. Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation. Front Pharmacol. 2022,13:1010483. doi: 10.3389/fphar.2022.1010483
    Read this paper
  • Lai CY, Hsieh MC, Ho YC, et al. GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription. Neuropharmacology. 2018,135:536-546. doi: 10.1016/j.neuropharm.2018.03.012
    Read this paper
  • Lin TB, Hsieh MC, Lai CY, et al. Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription. J Pineal Res. 2016,60(3):263-76. doi: 10.1111/jpi.12307
    Read this paper
  • Lin TB, Hsieh MC, Lai CY, et al. Modulation of Nerve Injury-induced HDAC4 Cytoplasmic Retention Contributes to Neuropathic Pain in Rats. Anesthesiology. 2015,123(1):199-212. doi: 10.1097/ALN.0000000000000663
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Western Blot analysis of HELA cells using HDAC4 Polyclonal Antibody
Product group Antibodies
Cusabio
HDAC4 AntibodyCSB-PA002881
ApplicationsWestern Blot, ELISA
ReactivityHuman, Mouse, Rat
TargetHDAC4
  • SizePrice
WB analysis of HeLa (1), Jurkat (2) cell lysate using GTX83229 HDAC4 antibody [7B2].
Product group Antibodies
GeneTex
HDAC4 antibody [7B2]GTX83229
ApplicationsWestern Blot, ELISA
TargetHDAC4
  • SizePrice
Product group Antibodies
GeneTex
HDAC4 antibody [HL3420]GTX641262
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetHDAC4
  • SizePrice
Product group Antibodies
MedChem Express
HDAC4 Antibody (YA391, Rabbit)HY-P80153
TargetHDAC4
  • SizePrice
ICC/IF analysis of HeLa cells using HDAC4 antibody at a dilution of 1:150.
Product group Antibodies
GeneTex
HDAC4 antibody [4A3-H7-C6]GTX49181
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetHDAC4
  • SizePrice
Product group Antibodies
GeneTex
HDAC4 antibodyGTX12170
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
TargetHDAC4
  • SizePrice
Product group Antibodies
GeneTex
HDAC4 antibodyGTX12172
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
TargetHDAC4
  • SizePrice
Product group Antibodies
Bethyl Laboratories
Rabbit anti-HDAC4 Antibody, Affinity PurifiedA303-467A
ApplicationsImmunoPrecipitation, Western Blot
TargetHDAC4
  • SizePrice
Product group Antibodies
RayBiotech
Anti-HDAC4 Antibody144-00179
ApplicationsWestern Blot, ImmunoHistoChemistry
TargetHDAC4
  • SizePrice
Figure 1. Western blot analysis of HDAC4 using anti-HDAC4 antibody (A00971-1). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human HEK293 whole cell lysates, Lane 2: human HELA whole cell lysates, Lane 3: human THP-1 whole cell lysates, Lane 4: human HEPG2 whole cell lysates, Lane 5: human U87 whole cell lysates, Lane 6: rat testis tissue lysates, Lane 7: mouse testis tissue lysates, Lane 8: mouse NIH/3T3 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-HDAC4 antigen affinity purified polyclonal antibody (Catalog # A00971-1) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for HDAC4 at approximately 140KD. The expected band size for HDAC4 is at 119KD.
Product group Antibodies
Boster Bio
Anti-HDAC4 Antibody Picoband(r)A00971-1-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetHDAC4
  • SizePrice